15 Day/15 Night Cruises out of San Diego, California

Are you looking for 15 day cruises that leave from San Diego, CA? As of today - September 19, 2026 - there are 4 such cruise options. These cruise options are offered by two cruise lines - Holland America (total of 3 sailings, 2 on Zaandam and 1 on Zuiderdam) and Royal Caribbean (just 1 sailing on Serenade of the Seas).

In the following table you can see all 15 day cruises that depart from San Diego sorted by departure date.
Zaandam December 19, 2026
From
$1,799
per person
$/Day:
$120
Duration:
15 Nights
Region:
Panama Canal
Depart:
San Diego
Arrive:
Ft. Lauderdale
Ship:
Zaandam
OnBoard Credit:
$150 - $400
Select
Zaandam December 19, 2026
Zuiderdam January 30, 2027
From
$1,749
per person
$/Day:
$117
Duration:
15 Nights
Region:
Panama Canal
Depart:
San Diego
Arrive:
Miami
Ship:
Zuiderdam
OnBoard Credit:
$150 - $400
Select
Zuiderdam January 30, 2027
Serenade of the Seas October 7, 2027
From
$2,057
per person
$/Day:
$138
Duration:
15 Nights
Region:
Panama Canal
Depart:
San Diego
Arrive:
Tampa
Ship:
Serenade of the Seas
OnBoard Credit:
$50
Select
Serenade of the Seas October 7, 2027
Zaandam December 18, 2027
From
$2,674
per person
$/Day:
$179
Duration:
15 Nights
Region:
Panama Canal
Depart:
San Diego
Arrive:
Miami
Ship:
Zaandam
Select
Zaandam December 18, 2027