16 Day/16 Night Cruises out of San Francisco, California

Are you looking for 16 day cruises that leave from San Francisco, CA? As of today - September 18, 2025 - there are 19 such cruise options. These cruise options are offered by just one cruise line - Princess (total of 19 sailings, 18 on Ruby Princess and 1 on Island Princess).

In the following table you can see all 16 day cruises that depart from San Francisco sorted by departure date.

Oct. 30, 2025

From

$1,499

per person

$/Day:

$94

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Dec. 1, 2025

From

$1,448

per person

$/Day:

$91

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Dec. 7, 2025

From

$1,539

per person

$/Day:

$96

Duration:

16 Nights

Region:

Panama Canal

Depart:

San Francisco

Arrive:

Ft. Lauderdale

Ship:

Island Princess

Select

Dec. 17, 2025

From

$1,599

per person

$/Day:

$100

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Jan. 2, 2026

From

$1,299

per person

$/Day:

$81

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Jan. 29, 2026

From

$1,298

per person

$/Day:

$81

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Feb. 19, 2026

From

$1,948

per person

$/Day:

$122

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Mar. 18, 2026

From

$1,298

per person

$/Day:

$81

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Apr. 3, 2026

From

$1,249

per person

$/Day:

$78

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Oct. 23, 2026

From

$1,848

per person

$/Day:

$116

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Nov. 8, 2026

From

$1,448

per person

$/Day:

$91

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Nov. 29, 2026

From

$1,598

per person

$/Day:

$100

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Dec. 26, 2026

From

$2,018

per person

$/Day:

$126

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Jan. 11, 2027

From

$1,578

per person

$/Day:

$99

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Jan. 27, 2027

From

$1,528

per person

$/Day:

$96

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Feb. 12, 2027

From

$1,628

per person

$/Day:

$102

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Feb. 28, 2027

From

$1,708

per person

$/Day:

$107

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Mar. 16, 2027

From

$1,728

per person

$/Day:

$108

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Apr. 1, 2027

From

$1,549

per person

$/Day:

$97

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select