16 Day/16 Night Cruises out of San Francisco, California

Are you looking for 16 day cruises that leave from San Francisco, CA? As of today - May 1, 2025 - there are 20 such cruise options. These cruise options are offered by two cruise lines - Princess (total of 19 sailings, 18 on Ruby Princess and 1 on Island Princess) and Carnival (just 1 sailing on Carnival Legend).

In the following table you can see all 16 day cruises that depart from San Francisco sorted by departure date.

Oct. 6, 2025

From

$1,243

$/Day:

$78

Duration:

16 Nights

Region:

Panama Canal

Depart:

San Francisco

Arrive:

Galveston

Ship:

Carnival Legend

Itinerary:

San Francisco to Galveston

Select

Oct. 30, 2025

From

$1,868

$/Day:

$117

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Dec. 1, 2025

From

$1,348

$/Day:

$84

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Dec. 7, 2025

From

$1,378

$/Day:

$86

Duration:

16 Nights

Region:

Panama Canal

Depart:

San Francisco

Arrive:

Ft. Lauderdale

Ship:

Island Princess

Itinerary:

San Francisco to Ft. Lauderdale

Select

Dec. 17, 2025

From

$1,798

$/Day:

$112

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Jan. 2, 2026

From

$1,558

$/Day:

$97

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Jan. 29, 2026

From

$1,348

$/Day:

$84

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Feb. 19, 2026

From

$1,698

$/Day:

$106

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Mar. 18, 2026

From

$1,298

$/Day:

$81

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Apr. 3, 2026

From

$1,548

$/Day:

$97

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Oct. 23, 2026

From

$1,728

$/Day:

$108

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Nov. 8, 2026

From

$1,728

$/Day:

$108

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Nov. 29, 2026

From

$1,398

$/Day:

$87

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Dec. 26, 2026

From

$2,038

$/Day:

$127

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Jan. 11, 2027

From

$1,598

$/Day:

$100

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Jan. 27, 2027

From

$1,598

$/Day:

$100

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Feb. 12, 2027

From

$1,648

$/Day:

$103

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Feb. 28, 2027

From

$1,778

$/Day:

$111

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Mar. 16, 2027

From

$1,648

$/Day:

$103

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select

Apr. 1, 2027

From

$1,618

$/Day:

$101

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Itinerary:

San Francisco Round Trip

Select