16 Day/16 Night Cruises out of San Francisco, California

Are you looking for 16 day cruises that leave from San Francisco, CA? As of today - November 12, 2025 - there are 18 such cruise options. These cruise options are offered by just one cruise line - Princess (total of 18 sailings, 17 on Ruby Princess and 1 on Island Princess).

In the following table you can see all 16 day cruises that depart from San Francisco sorted by departure date.

Dec. 1, 2025

From

$999

per person

$/Day:

$63

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Dec. 7, 2025

From

$1,219

per person

$/Day:

$77

Duration:

16 Nights

Region:

Panama Canal

Depart:

San Francisco

Arrive:

Ft. Lauderdale

Ship:

Island Princess

Select

Dec. 17, 2025

From

$1,399

per person

$/Day:

$88

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Jan. 2, 2026

From

$1,249

per person

$/Day:

$79

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Jan. 29, 2026

From

$1,399

per person

$/Day:

$88

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Feb. 19, 2026

From

$1,198

per person

$/Day:

$75

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Mar. 18, 2026

From

$1,415

per person

$/Day:

$89

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Apr. 3, 2026

From

$2,389

per person

$/Day:

$150

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Oct. 23, 2026

From

$1,659

per person

$/Day:

$104

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Nov. 8, 2026

From

$1,229

per person

$/Day:

$77

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Nov. 29, 2026

From

$1,598

per person

$/Day:

$100

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Dec. 26, 2026

From

$1,779

per person

$/Day:

$112

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Jan. 11, 2027

From

$1,559

per person

$/Day:

$98

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Jan. 27, 2027

From

$1,509

per person

$/Day:

$95

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Feb. 12, 2027

From

$1,609

per person

$/Day:

$101

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Feb. 28, 2027

From

$1,589

per person

$/Day:

$100

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Mar. 16, 2027

From

$1,609

per person

$/Day:

$101

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select

Apr. 1, 2027

From

$1,479

per person

$/Day:

$93

Duration:

16 Nights

Region:

Hawaii

Depart:

San Francisco

Arrive:

San Francisco

Ship:

Ruby Princess

Select