16 Day/16 Night Cruises out of San Francisco, California
Are you looking for 16 day cruises that leave from San Francisco, CA? As of today - November 12, 2025 - there are 18 such cruise options. These cruise options are offered by just one cruise line - Princess (total of 18 sailings, 17 on Ruby Princess and 1 on Island Princess).
In the following table you can see all 16 day cruises that depart from San Francisco sorted by departure date.