2019 Cruises out of San Diego, California |
| There are 54 cruises that depart from San Diego, CA in the year 2019. Four cruise lines offer cruises that leave out of San Diego in 2019 - Holland America (total of 46 sailings, among them 15 on Eurodam, 13 on Oosterdam and 8 on Nieuw Amsterdam), Carnival (total of 5 sailings, all of them on Carnival Miracle), Celebrity (total of 2 sailings, among them 1 on Celebrity Eclipse) and Royal Caribbean (just 1 sailing). You can see San Diego cruise schedule for 2019 in the table below. Be sure to look at the $/Day column to find cheap San Diego cruise deals in 2019. |
| Departure | Region | Itinerary | Ship | Days | Price | $/Day | Select |
| January 3 | Panama Canal | San Diego to Ft. Lauderdale | Volendam | 15 | $1,499 | $100 |  |
| January 6 | Mexico | San Diego Round Trip | Eurodam | 7 | $777 | $111 | |
| January 13 | Mexico | San Diego Round Trip | Eurodam | 7 | $749 | $107 | |
| January 20 | Mexico | San Diego Round Trip | Eurodam | 7 | $749 | $107 | |
| January 27 | Mexico | San Diego Round Trip | Eurodam | 7 | $749 | $107 | |
| February 2 | South America | San Diego to Lima | Volendam | 15 | $1,699 | $113 | |
| February 2 | South America | San Diego Round Trip | Volendam | 30 | $3,099 | $103 | |
| February 3 | Hawaii | San Diego Round Trip | Eurodam | 17 | $1,999 | $118 | |
| February 20 | Hawaii | San Diego Round Trip | Eurodam | 17 | $1,799 | $106 | |
| March 4 | Panama Canal | San Diego to Ft. Lauderdale | Volendam | 15 | $1,599 | $107 | |
| March 9 | Hawaii | San Diego Round Trip | Eurodam | 28 | $4,999 | $179 | |
| March 13 | Panama Canal | San Diego to Miami | Jewel of the Seas | 16 | $11,994 | $750 | |
| March 17 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $699 | $100 | |
| March 24 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $679 | $97 | |
| March 31 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $659 | $94 | |
| April 3 | Panama Canal | San Diego to Ft. Lauderdale | Volendam | 15 | $1,399 | $93 | |
| April 6 | Mexico | San Diego Round Trip | Eurodam | 7 | $629 | $90 | |
| April 7 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $629 | $90 | |
| April 8 | Pacific Coast | San Diego to Vancouver | Celebrity Eclipse | 9 | $899 | $100 | |
| April 13 | Hawaii | San Diego Round Trip | Eurodam | 16 | $2,099 | $131 | |
| April 13 | Hawaii | San Diego to Vancouver | Eurodam | 20 | $2,199 | $110 | |
| April 14 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $699 | $100 | |
| April 21 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $659 | $94 | |
| April 28 | Pacific Coast | San Diego to Vancouver | Nieuw Amsterdam | 6 | $699 | $117 | |
| April 29 | Pacific Coast | San Diego to Vancouver | Eurodam | 4 | $259 | $65 | |
| April 30 | Pacific Coast | San Diego to Vancouver | Oosterdam | 4 | $299 | $75 | |
| September 30 | South America | San Diego Round Trip | Amsterdam | 28 | $2,799 | $100 | |
| October 1 | Panama Canal | San Diego to Ft. Lauderdale | Volendam | 17 | $2,299 | $135 | |
| October 3 | Panama Canal | San Diego to Ft. Lauderdale | Nieuw Amsterdam | 16 | $2,199 | $137 | |
| October 6 | Mexico | San Diego Round Trip | Oosterdam | 7 | $699 | $100 | |
| October 13 | Mexico | San Diego Round Trip | Oosterdam | 7 | $699 | $100 | |
| October 13 | Hawaii | San Diego Round Trip | Oosterdam | 24 | $2,499 | $104 | |
| October 19 | Mexico | San Diego Round Trip | Eurodam | 7 | $699 | $100 | |
| October 20 | Hawaii | San Diego Round Trip | Oosterdam | 17 | $1,899 | $112 | |
| October 28 | Hawaii | San Diego Round Trip | Amsterdam | 51 | $7,749 | $152 | |
| November 2 | Mexico | San Diego Round Trip | Eurodam | 7 | $699 | $100 | |
| November 6 | Hawaii | San Diego Round Trip | Oosterdam | 17 | $1,999 | $118 | |
| November 6 | Hawaii | San Diego Round Trip | Oosterdam | 24 | $2,699 | $112 | |
| November 9 | Panama Canal | San Diego to Miami | Celebrity Infinity | 15 | $1,299 | $87 | |
| November 9 | Mexico | San Diego Round Trip | Eurodam | 7 | $699 | $100 | |
| November 16 | Panama Canal | San Diego to Ft. Lauderdale | Eurodam | 15 | $1,799 | $120 | |
| November 23 | Mexico | San Diego Round Trip | Oosterdam | 7 | $799 | $114 | |
| November 30 | Mexico | San Diego Round Trip | Oosterdam | 7 | $649 | $93 | |
| December 1 | Mexico | San Diego Round Trip | Carnival Miracle | 7 | $749 | $107 | |
| December 6 | Panama Canal | San Diego to Ft. Lauderdale | Rotterdam | 15 | $1,999 | $133 | |
| December 7 | Mexico | San Diego Round Trip | Oosterdam | 7 | $649 | $93 | |
| December 8 | Hawaii | San Diego Round Trip | Carnival Miracle | 14 | $1,549 | $111 | |
| December 14 | Mexico | San Diego Round Trip | Oosterdam | 7 | $649 | $93 | |
| December 18 | Panama Canal | San Diego to Ft. Lauderdale | Amsterdam | 17 | $3,399 | $200 | |
| December 21 | Mexico | San Diego Round Trip | Oosterdam | 7 | $1,299 | $186 | |
| December 22 | Mexico | San Diego Round Trip | Carnival Miracle | 5 | $749 | $150 | |
| December 27 | Mexico | San Diego Round Trip | Carnival Miracle | 3 | $534 | $178 | |
| December 28 | Mexico | San Diego Round Trip | Oosterdam | 7 | $1,299 | $186 | |
| December 30 | Mexico | San Diego Round Trip | Carnival Miracle | 4 | $654 | $164 | |