2019 Cruises out of San Diego, California |
| There are 45 cruises that depart from San Diego, CA in the year 2019. Four cruise lines offer cruises that leave out of San Diego in 2019 - Holland America (total of 37 sailings, among them 13 on Oosterdam, 9 on Eurodam and 8 on Nieuw Amsterdam), Carnival (total of 5 sailings, all of them on Carnival Miracle), Celebrity (total of 2 sailings, among them 1 on Celebrity Eclipse) and Royal Caribbean (just 1 sailing). You can see San Diego cruise schedule for 2019 in the table below. Be sure to look at the $/Day column to find cheap San Diego cruise deals in 2019. |
| Departure | Region | Itinerary | Ship | Days | Price | $/Day | Select |
| March 4 | Panama Canal | San Diego to Ft. Lauderdale | Volendam | 15 | $1,599 | $107 |  |
| March 9 | Hawaii | San Diego Round Trip | Eurodam | 28 | $4,999 | $179 | |
| March 13 | Panama Canal | San Diego to Miami | Jewel of the Seas | 16 | $11,672 | $730 | |
| March 17 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $810 | $116 | |
| March 24 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $699 | $100 | |
| March 31 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $559 | $80 | |
| April 3 | Panama Canal | San Diego to Ft. Lauderdale | Volendam | 15 | $1,399 | $93 | |
| April 6 | Mexico | San Diego Round Trip | Eurodam | 7 | $529 | $76 | |
| April 7 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $529 | $76 | |
| April 8 | Pacific Coast | San Diego to Vancouver | Celebrity Eclipse | 9 | $599 | $67 | |
| April 13 | Hawaii | San Diego Round Trip | Eurodam | 16 | $1,949 | $122 | |
| April 13 | Hawaii | San Diego to Vancouver | Eurodam | 20 | $2,049 | $102 | |
| April 14 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $549 | $78 | |
| April 21 | Mexico | San Diego Round Trip | Nieuw Amsterdam | 7 | $569 | $81 | |
| April 28 | Pacific Coast | San Diego to Vancouver | Nieuw Amsterdam | 6 | $499 | $83 | |
| April 29 | Pacific Coast | San Diego to Vancouver | Eurodam | 4 | $249 | $62 | |
| April 30 | Pacific Coast | San Diego to Vancouver | Oosterdam | 4 | $399 | $100 | |
| September 30 | South America | San Diego Round Trip | Amsterdam | 28 | $3,599 | $129 | |
| October 1 | Panama Canal | San Diego to Ft. Lauderdale | Volendam | 17 | $2,599 | $153 | |
| October 3 | Panama Canal | San Diego to Ft. Lauderdale | Nieuw Amsterdam | 16 | $2,499 | $156 | |
| October 6 | Mexico | San Diego Round Trip | Oosterdam | 7 | $699 | $100 | |
| October 13 | Hawaii | San Diego Round Trip | Oosterdam | 24 | $2,599 | $108 | |
| October 13 | Mexico | San Diego Round Trip | Oosterdam | 7 | $699 | $100 | |
| October 19 | Mexico | San Diego Round Trip | Eurodam | 7 | $699 | $100 | |
| October 20 | Hawaii | San Diego Round Trip | Oosterdam | 17 | $2,199 | $129 | |
| October 28 | Hawaii | San Diego Round Trip | Amsterdam | 51 | $8,399 | $165 | |
| November 2 | Mexico | San Diego Round Trip | Eurodam | 7 | $699 | $100 | |
| November 6 | Hawaii | San Diego Round Trip | Oosterdam | 24 | $2,699 | $112 | |
| November 6 | Hawaii | San Diego Round Trip | Oosterdam | 17 | $2,199 | $129 | |
| November 9 | Panama Canal | San Diego to Miami | Celebrity Infinity | 15 | $1,379 | $92 | |
| November 9 | Mexico | San Diego Round Trip | Eurodam | 7 | $699 | $100 | |
| November 16 | Panama Canal | San Diego to Ft. Lauderdale | Eurodam | 15 | $2,199 | $147 | |
| November 23 | Mexico | San Diego Round Trip | Oosterdam | 7 | $799 | $114 | |
| November 30 | Mexico | San Diego Round Trip | Oosterdam | 7 | $749 | $107 | |
| December 1 | Mexico | San Diego Round Trip | Carnival Miracle | 7 | $749 | $107 | |
| December 6 | Panama Canal | San Diego to Ft. Lauderdale | Rotterdam | 15 | $1,999 | $133 | |
| December 7 | Mexico | San Diego Round Trip | Oosterdam | 7 | $749 | $107 | |
| December 8 | Hawaii | San Diego Round Trip | Carnival Miracle | 14 | $1,549 | $111 | |
| December 14 | Mexico | San Diego Round Trip | Oosterdam | 7 | $749 | $107 | |
| December 18 | Panama Canal | San Diego to Ft. Lauderdale | Amsterdam | 17 | $3,399 | $200 | |
| December 21 | Mexico | San Diego Round Trip | Oosterdam | 7 | $1,299 | $186 | |
| December 22 | Mexico | San Diego Round Trip | Carnival Miracle | 5 | $749 | $150 | |
| December 27 | Mexico | San Diego Round Trip | Carnival Miracle | 3 | $534 | $178 | |
| December 28 | Mexico | San Diego Round Trip | Oosterdam | 7 | $1,299 | $186 | |
| December 30 | Mexico | San Diego Round Trip | Carnival Miracle | 4 | $654 | $164 | |