2022 Cruises out of San Juan, Puerto Rico |
| There are 40 cruises that depart from San Juan, PR in the year 2022. Just two cruise lines offer cruises that leave out of San Juan in 2022 - Royal Caribbean (total of 25 sailings, 17 on Explorer of the Seas and 8 on Voyager of the Seas) and Norwegian (NCL) (total of 15 sailings, all of them on Norwegian Epic). You can see San Juan cruise schedule for 2022 in the table below. Be sure to look at the $/Day column to find cheap San Juan cruise deals in 2022. |
| Departure | Region | Itinerary | Ship | Days | Price | $/Day | Select |
| January 2 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $622 | $89 |  |
| January 2 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $694 | $99 | |
| January 9 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $657 | $94 | |
| January 9 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $594 | $85 | |
| January 16 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $622 | $89 | |
| January 16 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $564 | $81 | |
| January 23 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $622 | $89 | |
| January 23 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $714 | $102 | |
| January 30 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $622 | $89 | |
| January 30 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $704 | $101 | |
| February 6 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $564 | $81 | |
| February 6 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $622 | $89 | |
| February 13 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $601 | $86 | |
| February 13 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $615 | $88 | |
| February 20 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $664 | $95 | |
| February 20 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $714 | $102 | |
| February 27 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $664 | $95 | |
| February 27 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $564 | $81 | |
| March 6 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $664 | $95 | |
| March 6 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $515 | $74 | |
| March 13 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $713 | $102 | |
| March 13 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $514 | $73 | |
| March 20 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $713 | $102 | |
| March 20 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $814 | $116 | |
| March 27 | Caribbean | San Juan to New York | Norwegian Epic | 6 | $699 | $117 | |
| March 27 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $615 | $88 | |
| April 3 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $674 | $96 | |
| April 10 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $713 | $102 | |
| April 17 | Caribbean | San Juan Round Trip | Explorer of the Seas | 7 | $732 | $105 | |
| April 24 | Caribbean | San Juan to Miami | Explorer of the Seas | 6 | $663 | $111 | |
| November 6 | Caribbean | San Juan Round Trip | Voyager of the Seas | 7 | $559 | $80 | |
| November 13 | Caribbean | San Juan Round Trip | Voyager of the Seas | 7 | $611 | $87 | |
| November 20 | Caribbean | San Juan Round Trip | Voyager of the Seas | 7 | $645 | $92 | |
| November 27 | Caribbean | San Juan Round Trip | Voyager of the Seas | 7 | $611 | $87 | |
| December 4 | Caribbean | San Juan Round Trip | Voyager of the Seas | 7 | $611 | $87 | |
| December 11 | Caribbean | San Juan Round Trip | Voyager of the Seas | 7 | $559 | $80 | |
| December 18 | Caribbean | San Juan Round Trip | Voyager of the Seas | 5 | $571 | $114 | |
| December 23 | Caribbean | San Juan Round Trip | Norwegian Epic | 7 | $944 | $135 | |
| December 30 | Caribbean | San Juan Round Trip | Norwegian Epic | 9 | $1,392 | $155 | |
| December 30 | Caribbean | San Juan Round Trip | Voyager of the Seas | 7 | $1,159 | $166 | |