2025 Cruises out of San Francisco, California

There are 5 cruises that depart from San Francisco, CA in the year 2025. Only one cruise line offers cruises that leave out of San Francisco in 2025 - Princess (total of 5 sailings, 4 on Ruby Princess and 1 on Island Princess).

You can see San Francisco cruise schedule for 2025 in the table below. Be sure to look at the $/Day column to find cheap San Francisco cruise deals in 2025.
Ruby Princess November 15, 2025
November 15
From
$749
per person
$/Day:
$69
Duration:
11 Nights
Region:
Mexico
Depart:
San Francisco
Arrive:
San Francisco
Ship:
Ruby Princess
Select
Ruby Princess November 15, 2025
Ruby Princess November 26, 2025
November 26
From
$990
per person
$/Day:
$198
Duration:
5 Nights
Region:
Pacific Coast
Depart:
San Francisco
Arrive:
San Francisco
Ship:
Ruby Princess
Select
Ruby Princess November 26, 2025
Ruby Princess December 1, 2025
December 1
From
$999
per person
$/Day:
$63
Duration:
16 Nights
Region:
Hawaii
Depart:
San Francisco
Arrive:
San Francisco
Ship:
Ruby Princess
Select
Ruby Princess December 1, 2025
Island Princess December 7, 2025
December 7
From
$1,219
per person
$/Day:
$77
Duration:
16 Nights
Region:
Panama Canal
Depart:
San Francisco
Arrive:
Ft. Lauderdale
Ship:
Island Princess
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Island Princess December 7, 2025
Ruby Princess December 17, 2025
December 17
From
$1,399
per person
$/Day:
$88
Duration:
16 Nights
Region:
Hawaii
Depart:
San Francisco
Arrive:
San Francisco
Ship:
Ruby Princess
Select
Ruby Princess December 17, 2025