There are 3 cruises that depart from San Francisco, CA in the year 2025. Only one cruise line offers cruises that leave out of San Francisco in 2025 - Princess (total of 3 sailings, 2 on Ruby Princess and 1 on Island Princess).
You can see San Francisco cruise schedule for 2025 in the table below. Be sure to look at the $/Day column to find cheap San Francisco cruise deals in 2025.
