4 Day/4 Night Cruises out of San Diego, California

Are you looking for 4 day cruises that leave from San Diego, CA? As of today - November 2, 2025 - there are 7 such cruise options. These cruise options are offered by two cruise lines - Holland America (total of 4 sailings, among them 1 on Zaandam, 1 on Eurodam and 1 on Koningsdam) and Royal Caribbean (just 3 sailings, all of them on Serenade of the Seas).

In the following table you can see all 4 day cruises that depart from San Diego sorted by departure date.

Apr. 20, 2026

From

$399

per person

$/Day:

$100

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Eurodam

Select

May. 2, 2026

From

$399

per person

$/Day:

$100

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Zaandam

Select

Oct. 11, 2026

From

$497

per person

$/Day:

$125

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Nov. 29, 2026

From

$465

per person

$/Day:

$117

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Dec. 6, 2026

From

$465

per person

$/Day:

$117

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Apr. 3, 2027

From

$494

per person

$/Day:

$124

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Koningsdam

Select

Apr. 28, 2027

From

$514

per person

$/Day:

$129

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Nieuw Amsterdam

Select