4 Day/4 Night Cruises out of San Diego, California

Are you looking for 4 day cruises that leave from San Diego, CA? As of today - May 17, 2026 - there are 5 such cruise options. These cruise options are offered by two cruise lines - Royal Caribbean (just 3 sailings, all of them on Serenade of the Seas) and Holland America (total of 2 sailings, 1 on Koningsdam and 1 on Nieuw Amsterdam).

In the following table you can see all 4 day cruises that depart from San Diego sorted by departure date.

Oct. 11, 2026

From

$396

per person

$/Day:

$99

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Nov. 29, 2026

From

$380

per person

$/Day:

$95

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Dec. 6, 2026

From

$394

per person

$/Day:

$99

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Apr. 3, 2027

From

$434

per person

$/Day:

$109

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Koningsdam

Select

Apr. 28, 2027

From

$479

per person

$/Day:

$120

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Nieuw Amsterdam

Select