4 Day/4 Night Cruises out of San Diego, California

Are you looking for 4 day cruises that leave from San Diego, CA? As of today - August 18, 2026 - there are 18 such cruise options. These cruise options are offered by two cruise lines - Royal Caribbean (total of 15 sailings, all of them on Serenade of the Seas) and Holland America (total of 3 sailings, 2 on Koningsdam and 1 on Nieuw Amsterdam).

In the following table you can see all 4 day cruises that depart from San Diego sorted by departure date.

Oct. 11, 2026

From

$340

per person

$/Day:

$85

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Nov. 29, 2026

From

$330

per person

$/Day:

$83

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Dec. 6, 2026

From

$320

per person

$/Day:

$80

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Jan. 10, 2027

From

$300

per person

$/Day:

$75

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Jan. 17, 2027

From

$319

per person

$/Day:

$80

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Jan. 24, 2027

From

$319

per person

$/Day:

$80

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Feb. 7, 2027

From

$319

per person

$/Day:

$80

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Feb. 14, 2027

From

$330

per person

$/Day:

$83

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Feb. 21, 2027

From

$330

per person

$/Day:

$83

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Mar. 7, 2027

From

$349

per person

$/Day:

$88

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Mar. 14, 2027

From

$350

per person

$/Day:

$88

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Mar. 21, 2027

From

$346

per person

$/Day:

$87

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Apr. 3, 2027

From

$449

per person

$/Day:

$113

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Koningsdam

Select

Apr. 4, 2027

From

$449

per person

$/Day:

$113

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Apr. 11, 2027

From

$449

per person

$/Day:

$113

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Apr. 18, 2027

From

$449

per person

$/Day:

$113

Duration:

4 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Serenade of the Seas

Select

Apr. 28, 2027

From

$429

per person

$/Day:

$108

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Nieuw Amsterdam

Select

Apr. 8, 2028

From

$544

per person

$/Day:

$136

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Koningsdam

Select